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人工智能显微成像能够高效检测稀有事件
对稀有事件进行定位和选择性成像是许多生物样本研究过程的关键。然而,由于时间限制和高度的复杂性,有些实验无法做到,从而限制了获得新发现的前景。通过基于人工智能的显微成像检测稀有事件,这种工作流程将智能样本导航、图像采集工具和人工智能驱动的图像分析等不同功能融合起来共同协作,能够克服上述局限性。
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Central Nervous System (CNS) Development and Activity in Organisms
This article shows how studying central nervous system (CNS) development in Drosophila-melanogaster embryos expressing a GCaMP calcium indicator in the neurons can be improved with a THUNDER Imager.
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不同组织样品制备方法的RNA质量
本文介绍了样品制备过程和紫外激光显微切片(UV LMD)对小鼠脑组织冷冻切片RNA质量的影响。为在提取RNA时获取良好的结果,从高品质组织开始并在处理前后检查RNA质量至关重要。RNA完整性指数(RIN)以1到10的等级标准来显示样品质量。简言之,RIN数值越高,RNA质量越高。这项研究结果表明,可以利用紫外激光显微切片技术,可以从单个组织细胞中获取品质稳定的RNA。
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快速、高灵敏度成像和人工智能辅助分析
The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However,…
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Find Relevant Specimen Details from Overviews
Switch from searching image by image to seeing the full overview of samples quickly and identifying the important specimen details instantly with confocal microscopy. Use that knowledge to set up…
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High-resolution 3D Imaging to Investigate Tissue Ageing
Award-winning researcher Dr. Anjali Kusumbe demonstrates age-related changes in vascular microenvironments through single-cell resolution 3D imaging of young and aged organs.
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如何让样品保持在生理状态
Coral Life工作流将动态数据与最佳的样品固定方式(高压冷冻)相结合。然而,如果您的细胞因为温度下降,或缺氧气、二氧化碳或营养物质缺乏而受到损伤,那么再好的样品保存也没有意义。这些因素将影响一系列的生物过程,甚至破坏原超微结构基础,影响您的分析。