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常规实验室显微镜 - 正置显微镜

用于生命科学研究的正置光学显微镜

使用徕卡显微镜,在生命科学研究领域,你能得到可供文章发表级别的清晰成像和个性化定制的正置显微镜解决方案。这些强大的成像系统拥有恒定颜色,自然光照明,高端光学器件以及可配置的选项,为您提供高对比,清晰明亮的图像,助力您尖端生物学研究。

用于工业和材料学的正置光学显微镜

从徕卡显微系统的工业及材料正置显微镜中获取最细微的细节,并有效地检查和记录结果。每一个解决方案可以与明亮恒温的LED照明,人体工学配件,先进的数码相机和直观的软件进行搭配以满足广泛的应用范围。

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作为徕卡显微系统有限公司 的信息门户,ScienceLab (徕卡课堂) 提供许多关于显微技术主题的科研和教学材料。其内容宗旨在于为初学者、有经验的从业者和科学家等的日常工作和实验提供支持。

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Cell DIVE multiplexed image of FFPE tissue section from human invasive ductal carcinoma (IDC)

人工智能驱动的乳腺癌研究多重染色成像空间分析工具

乳腺癌(BC)是女性因癌症死亡的主要原因,研究查肿瘤微环境(TME)对于阐明肿瘤进展机制至关重要。利用超多标染色空间蛋白质组学技术系统地绘制肿瘤微环境图谱可以提高精准免疫肿瘤学的能力。在这里,我们将基于人工智能的高倍空间分析应用于BC组织,研究免疫细胞类型和生物标记物,从而深入了解受免疫疗法反应的TME分子机制。
67-hour, multi-position time-lapse of mouse intestinal organoids expressing the cell cycle reporter FUCCI2 (hGem-mVenus and hCdt1-mCherry).

Focus on Long-Term Imaging in 3D with Light Sheet Microscopy

Long-term 3D imaging reveals how complex multicellular systems grow and develop and how cells move and interact over time, unlocking critical insights into development, disease, and regeneration.…
Aneurysm shown with GLOW800 AR fluorescence application. Image courtesy of Prof. Jacques Guyotat, Hôpital Neurologique Pierre Wertheimer, Lyon

荧光在血管神经外科中的应用前景

在血管神经外科手术中,手术显微镜用于提供手术区域的放大和照明视图。尽管显微镜提供的图像质量和光学放大倍率让外科医生受益匪浅,但外科医生必须依靠自己对色彩的敏锐感知来区分不同类型的组织。
TEM micrographs of polymer sections. Left: Poly(styrene)-b-poly(isoprene). Right: Poly(styrene)-b-poly(methyl methacrylate).

Ultramicrotome Sectioning of Polymers for TEM Analysis

We demonstrate the capabilities of the UC Enuity ultramicrotome from Leica Microsystems for preparing ultrathin sections of polymer samples under both ambient and cryogenic conditions. By presenting…
用 Leica 显微镜使用圆偏振光对径向生长的糖晶体进行成像。

偏振光显微镜影像图集

偏振光显微镜(又称为偏光显微镜)是一种应用于不同领域的重要方法,包括研究和质量保证。它不仅仅是在高倍率和高分辨率下产生图像,这通常是用普通光学显微镜完成的。 通过检查样本的形状、结构、颜色、双折射和进一步的光学性质,可以获得有关样本结构、光学性质和成分的附加信息。
Artificial Intelligence (AI) segmentation used in conjunction with LMD to increase discovery throughput.

Biomarker Discovery with Laser Microdissection

Explore the potential of spatial proteomics workflows, such as Deep Visual Proteomics (DVP), to decipher pathology mechanisms and uncover druggable targets. Altered protein expression, abundance, or…
Final Segmentation of organelles in Trichomonas species. Magenta – costa, light blue – hydrogenosomes, turquoise – ER, red – vacuoles, yellow – axostyle, green – Golgi apparatus.  Sample courtesy of Isabelle Guerin-Bonne, Low Kay En, Electron Microscopy Unit, Yong Loo Lin School of Medicine, National University of Singapore. Scale bar: 1 µm.

Volume EM and AI Image Analysis

The article outlines a detailed workflow for studying biological tissues in three dimensions using volume-scanning electron microscopy (volume-SEM) combined with AI-assisted image analysis. The focus…
Image of roundworm C. elegans acquired with a M205 FA fluorescence automated stereo microscope in combination with Rottermann contrast. Areas labelled with mCherry are seen as reddish purple.

A Guide to C. elegans Research – Working with Nematodes

Efficient microscopy techniques for C. elegans research are outlined in this guide. As a widely used model organism with about 70% gene homology to humans, the nematode Caenorhabditis elegans (also…

How a Breakthrough in Spatial Proteomics Saved Lives

Toxic epidermal necrolysis (TEN) is a rare but devastating reaction to common medications like antibiotics or gout treatments. It begins innocuously, often as a rash, but can escalate rapidly into…
Dr. Andrew Huang, Baylor College of Medicine, in the operating room (OR) performing ear, nose and throat (ENT) surgery using the MyVeo surgical visualization headset.

A Microvascular Surgeon’s View: How MyVeo Transforms Visualization

In this article, Dr. Andrew T. Huang, MD, FACS, otolaryngologist and a head and neck reconstructive surgeon, shares how digital 3D surgical visualization with the MyVeo headset from Leica Microsystems…

材料科学与检测

出色的样品制备和成像方法是可靠、准确地检测材料和观察细节的关键。与正置显微镜相比,倒置显微镜能让您以更高效的方式实现这一目标。倒置显微镜可为您提供高质量的光学镜组和智能自动化,从而实现理想的工作流程。

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生命科学研究

徕卡(Leica)生命科学显微镜凭借先进的创新和专业技术能力,支持观察、测量和分析微结构的成像要求。徕卡显微系统对科学应用领域的高度关注,使徕卡显微系统的用户始终保持领先位置

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