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常规实验室显微镜 - 正置显微镜

用于生命科学研究的正置光学显微镜

使用徕卡显微镜,在生命科学研究领域,你能得到可供文章发表级别的清晰成像和个性化定制的正置显微镜解决方案。这些强大的成像系统拥有恒定颜色,自然光照明,高端光学器件以及可配置的选项,为您提供高对比,清晰明亮的图像,助力您尖端生物学研究。

用于工业和材料学的正置光学显微镜

从徕卡显微系统的工业及材料正置显微镜中获取最细微的细节,并有效地检查和记录结果。每一个解决方案可以与明亮恒温的LED照明,人体工学配件,先进的数码相机和直观的软件进行搭配以满足广泛的应用范围。

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作为徕卡显微系统有限公司 的信息门户,ScienceLab (徕卡课堂) 提供许多关于显微技术主题的科研和教学材料。其内容宗旨在于为初学者、有经验的从业者和科学家等的日常工作和实验提供支持。

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Brain organoid labeled with lamin (green) and tubulin (magenta), acquired using Viventis Deep. Courtesy of Akanksha Jain, Treutlein Lab ETH-DBSSE Basel (Switzerland).

如何深入了解类器官和细胞球模型

在本电子书中,您将了解3D细胞培养模型(如类器官和细胞球)成像的关键注意事项。探索创新型显微镜解决方案,来实时记录类器官和细胞球的动态成像过程。
Waffle method lamella preparation and cryo-ET results - Representative workflow and results of lamella preparation from a vitrified C. elegans L1 larva using the waffle method. Image courtesy: Prof. Dr. Jürgen M. Plitzko - doi.org/10.1038/s41592-023-02113-5-

Waffle Method Workflow: From HPF to Cryo-ET Lamellae

Waffle freezing provides an HPF-based route to cryo-ET sample preparation. This workflow guide follows the process from grid and carrier assembly to vitrification, cryo-FIB milling, lamella…
Large field of view (FOV) 2D slices of a 1 mm diameter midbrain neural organoid stained with DAPI (blue, nuclear stain), β-tubulin (green, neuronal stain), and GFAP (red, astrocyte stain). Acquired on THUNDER Imager Cell with 10x magnification. Left: Raw widefield image, Right: THUNDER cleared image. Scale bar 400 μm. Sample courtesy of Dr Tanya Singh, University of Oxford, UK.

Fast, High-Contrast Widefield Imaging of Optically Challenging Samples

Live‑cell imaging of large, complex biological samples often requires large fields of view, sub-cellular resolution, high-sensitivity, and fast acquisition – all while maintaining low illumination…
Hunched working position without a microscope (left) and upright neutral posture achieved with the M320 dental microscope (right).

Dental Loupes vs Microscopes: Exploring Visualization Options in Dentistry

Dental professionals often ask: “Should I use dental loupes or invest in a microscope?” This article explores the key differences between dental microscopes and dental loupes, focusing on…
Low-input spatial proteomics workflow for megakaryocyte isolation from bone marrow.

Spatial Proteomics Workflow in Blood Cancer (MPNs)

Megakaryocytes play a central role in the biology of myeloproliferative neoplasms (MPNs), yet their in vivo proteomic characterization remains a major challenge due to low abundance and disrupted…
The M320 dental microscope.

选择牙科显微镜时需考虑的六大特性

在牙医学中,手术显微镜对于进行高质量和成功的手术来说变得愈发重要,尤其是在牙髓病学领域。显微镜协助牙医进行微创手术,旨在保护牙质、保留组织、最大限度地降低风险并缩短愈合时间。 要选择适合牙医需求的显微镜,了解现代牙科显微镜的一些决定性特征将十分有帮助。
Long-term in toto imaging of FUCCI2 intestinal organoids.

Multiscale Imaging of Organoids: High Content to Light Sheet

Learn multiscale organoid imaging: fixed high content phenotyping, gentle dual view light sheet, and reproducible pipelines that turn 3D data into insights.
Snapshot from a time lapse of a calcium imaging experiment using the ratiometric calcium indicator Fura-2.

比例成像

细胞的许多基本功能在很大程度上依赖于离子(例如钙、镁)、电压势和细胞质与周围细胞外空间之间的 pH 值的微妙但动态的平衡。这些平衡的变化会显著改变细胞的行为和功能。因此,实时测量细胞内离子、电压和 pH…
Ribbon diagram of a donor (D) and acceptor (A) molecule which participate in FRET (Förster resonance energy transfer).

荧光寿命成像与荧光共振能量转移

荧光寿命是荧光团在发射荧光光子返回基态之前保持其激发态的平均时间长度。这取决于荧光团的分子组成和纳米环境。 FLIM将寿命测量与成像相结合:对每个图像像素以测得的荧光寿命进行颜色编码,产生额外的图像反差。因此,FLIM可以提供关于荧光分子空间分布的信息和有关其生化状态或纳米环境的信息。…
Proveo 8x 3D digital microscope used in ophthalmic surgery, illustrating heads‑up visualization and clinical collaboration.

4 Key Benefits of 3D Digital Microscopy in Ophthalmic Surgery

3D digital visualization is rapidly transforming ophthalmic surgery. Modern 3D surgical microscopes enable surgeons to perform procedures using high-resolution digital displays rather than traditional…

材料科学与检测

出色的样品制备和成像方法是可靠、准确地检测材料和观察细节的关键。与正置显微镜相比,倒置显微镜能让您以更高效的方式实现这一目标。倒置显微镜可为您提供高质量的光学镜组和智能自动化,从而实现理想的工作流程。

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生命科学研究

徕卡(Leica)生命科学显微镜凭借先进的创新和专业技术能力,支持观察、测量和分析微结构的成像要求。徕卡显微系统对科学应用领域的高度关注,使徕卡显微系统的用户始终保持领先位置

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