偏振光显微镜影像图集
偏振光显微镜(又称为偏光显微镜)是一种应用于不同领域的重要方法,包括研究和质量保证。它不仅仅是在高倍率和高分辨率下产生图像,这通常是用普通光学显微镜完成的。
通过检查样本的形状、结构、颜色、双折射和进一步的光学性质,可以获得有关样本结构、光学性质和成分的附加信息。
Biomarker Discovery with Laser Microdissection
Explore the potential of spatial proteomics workflows, such as Deep Visual Proteomics (DVP), to decipher pathology mechanisms and uncover druggable targets.
Altered protein expression, abundance, or…
A Guide to C. elegans Research – Working with Nematodes
Efficient microscopy techniques for C. elegans research are outlined in this guide. As a widely used model organism with about 70% gene homology to humans, the nematode Caenorhabditis elegans (also…
A Novel Laser-Based Method for Studying Optic Nerve Regeneration
Optic nerve regeneration is a major challenge in neurobiology due to the limited self-repair capacity of the mammalian central nervous system (CNS) and the inconsistency of traditional injury models.…
How to Select the Right Measurement Microscope
With a measurement microscope, users can measure the size and dimensions of sample features in both 2D and 3D, something crucial for inspection, QC, failure analysis, and R&D. However, choosing the…
罕见疾病 CRISPR 疗法的开发与风险解除
Fyodor Urnov博士和Sadik Kassim博士最初是在ASGCT 2025会议上作这一按需演讲的,演讲的重点是遗传医学中的一个关键挑战:如何将CRISPR疗法从单一疾病解决方案扩展到平台方法,特别是针对罕见的儿科遗传疾病。Urnov 博士展示了由 Matthew Kan 博士领导的创新基因组研究所的工作,这是 IGI-Danaher Beacon for CRISPR Cures…
显微镜测量校准:为什么要校准以及如何校准
显微镜校准可确保用于检测、质量控制 (QC)、故障分析和研发 (R&D) 的测量结果准确一致。本文介绍了校准步骤。使用参照物进行校准可获得可重复的结果,并有助于确保与准则和标准一致。为获得准确一致的结果,建议校准显微镜并定期检查。如有需要,可向校准专家寻求支持。
多重成像揭示结肠癌的肿瘤免疫格局
由于抗药性和复发,癌症免疫疗法获益者寥寥无几,而针对癌症免疫周期多个步骤的组合治疗策略可能会改善治疗效果。这项研究表明,高通量空间蛋白质组学可用于识别细胞生物标志物之间的相互作用,并通过绘制肿瘤免疫微环境图来指导精准的组合疗法。
A Guide to Using Microscopy for Drosophila (Fruit Fly) Research
The fruit fly, typically Drosophila melanogaster, has been used as a model organism for over a century. One reason is that many disease-related genes are shared between Drosophila and humans. It is…