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Leica MZ10 F 荧光成像的模块化体视显微镜

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Comparison when observing a rodent model organism with a Greenough versus CMO (common main objective) stereo microscope for a task like surgery.

Rodent and Small-Animal Surgery

Learn how you can perform rodent (mouse, rat, hamster) and small-animal surgery efficiently with a microscope for developmental biology and medical research applications by reading this article.
Transgenic zebrafish larva where fluorescent proteins label the heart muscle blue, blood and blood vessels red, and all circulatory system cells green. Image recorded with a M205 FA microscope.

Imaging and Analyzing Zebrafish, Medaka, and Xenopus

Discover how to image and analyze zebrafish, medaka, and Xenopus frog model organisms efficiently with a microscope for developmental biology applications from this article.
[Translate to chinese:] SPERM HY-LITER™ staining of a sexual assault smear slide performed by forensic DNA crime laboratory.

对性侵证据中的精子进行法医检测

现代科学方法对于犯罪现场证据分析的影响为法医学的多个子领域带来了极大的改变。最为引人注目的一个例子或许就是分子生物学对于生物证据分析的影响。

应用的领域

荧光

荧光是生物和分析显微镜中最常用的物理现象之一,主要是因为它具有灵敏度高、特异性强的特点。荧光是冷发光的一种形式。用户可以通过显微镜来捕捉单个荧光分子的种类、分布、数量及其在细胞内的定位。用户可以进行荧光分子共定位和相互作用的研究,也可以观察在细胞内和细胞间运作离子浓度的变化,如胞吞和胞吐。借助超高分辨显微镜,我们甚至可以对亚细胞器的结构进行成像。
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