徕卡显微系统的显微镜、成像和分析解决方案

我们通过提供突破性的光学和数字化解决方案，赋能客户，洞见未来。175 多年来，我们在生命科学研究、工业、医学、法医学和教育等领域锐意创新，将可视化和分析技术推向更高，助力明智决策、优化工作流程

瞰见未知，同创世界健康与美好。

多元业务提升洞察

医疗

全方位产品组合赋能眼科、神经外科、耳鼻喉科、整形外科和口腔科等，总有一款能够满足您的需求。

生命科学研究

通过突破分辨率、速度和信息维度的极限，让科学家能够获得前所未有的洞察力，从而推动科学探索，成就生命无限潜能。

工业显微技术

通过以工作流为中心的创新科技，我们提供高质量和易于使用的解决方案，使用户能够在材料研究、产品研发和生产制造方面获得洞察力和投资回报。

[Translate to chinese:] Ivesta 3 Greenough Stereo Microscopes

Ivesta 3 格林诺夫体视显微镜

如果您可以提高检查效率并以一致的方式工作呢?

对于制造商或供应商来说，提高检查效率是头等大事。使用Ivesta 3格林诺夫立体显微镜，您可以优化目视检查和返工流程，同时获得可靠、一致的结果

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图像分析软件

Aivia：人工智能显微成像的未来

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Advanced Imaging – DMi8 倒置显微镜

使用 DMi8 倒置显微镜可简化复杂的显微成像工作流程。

们可根据您的研究需求和预算提供量身定制的平台解决方案，助您生成高质量的数据。

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阅读我们的最新文章

徕卡显微系统的知识门户网站提供有关显微镜学的科学研究资料和教学材料。网站内容专门面向初学者、经验丰富的从业者和科学家，为他们的日常工作和实验提供支持。

Aneurysm Clipping: Assessing Perforators in Real-time with AR Fluorescence

This article covers two aneurysm clipping cases highlighting the clinical benefits of GLOW800 Augmented Reality Fluorescence application in neurosurgery, based on insights from Prof. Tohru Mizutani,…

Prof. Fontana uses the Proveo 8 with EnFocus intraoperative OCT for his corneal surgery.

How does Real-time OCT Imaging Impact Precision in Corneal Surgery?

Corneal surgery is a highly specialized field. It requires great surgical precision to overcome challenges such as visualizing clearly the full anterior chamber, performing Descemet membrane peeling…

GLOW400 AR Fluorescence in anatomy view, image courtesy of Prof. Kondo

How to Achieve Brain Tissue Resection with GLOW400 AR

Intraoperative MRI is one form of real-time intraoperative visualization, but if more in-depth visualization to identify a tumor during surgery is wanted, intraoperative fluorescence diagnostics is…

[Translate to chinese:] Block-face created by automatic trimming under fluorescence. Mammalian cells of interest, stained with CellTrackerTM Green are visualized within the block-face using the UC Enuity equipped with the stereo microscope M205 FA. In the background a carbon finder grid in black is visible. All samples in the article are created by Felix Gaedke, PhD, CECAD, Cologne, Germany.

如何在块面中自动获取感兴趣的荧光细胞

本文介绍了使用超薄切片超薄切片机自动修整修块功能，获取树脂块面中带有荧光信号的细胞结构。我们展示了如何使用配置有体视显微镜 M205 FA 的超薄切片超薄切片机 UC Enuity ，来识别感兴趣的荧光细胞，如何自动修整包含细胞的块面，以及如何在切片中观察细胞而无需转移到外部显微镜。

Automated Laser Microdissection for Proteome Analysis

组织中的精密空间蛋白质组学信息

尽管可使用基于成像和质谱的方法进行空间蛋白质组学研究，但是图像与单细胞分辨率蛋白丰度测量值的关联仍然是个巨大的挑战。最近引入的一种方法，深层视觉蛋白质组学（DVP），将细胞表型的人工智能图像分析与自动化的单细胞或单核激光显微切割及超高灵敏度的质谱分析结合在了一起。DVP在保留空间背景的同时，将蛋白丰度与复杂的细胞或亚细胞表型关联在一起。

[Translate to chinese:] These images show the microstructure of a hard metal with 10% cobalt which is used for heavy-duty tools. The large increase in magnification of the right image (compared to the left) has a risk of being outside the useful range or, in other words, empty magnification.

当心“无效”放大率

在一个最简化的情况，光学显微镜由一个靠近标本的透镜（物镜）和一个靠近眼睛的透镜（目镜）组成。显微镜放大率是两个显微镜透镜系数的乘积。比如，40倍物镜和10倍目镜可以得到400倍放大率。

Developing embryos of different species at different stages during the elongation of their posterior body axis, from left to right in developmental time. The labelled regions in red depict a region of undifferentiated cells called the tailbud, with the corresponding region generated from that tissue shaded in grey. Upper row: lamprey; middle row: catshark; bottom row, zebrafish. This figure has been adapted from the following publication: Steventon, B., Duarte, F., Lagadec, R., Mazan, S., Nicolas, J.-F., & Hirsinger, E. (2016). Species tailoured contribution of volumetric growth and tissue convergence to posterior body elongation in vertebrates. Development, 2016. 143(10):1732-41

How to Study Gene Regulatory Networks in Embryonic Development

Join Dr. Andrea Boni by attending this on-demand webinar to explore how light-sheet microscopy revolutionizes developmental biology. This advanced imaging technique allows for high-speed, volumetric…

[Translate to chinese:] Multiplexed Cell DIVE imaging of Adult Human Alzheimer’s brain tissue section demonstrating expression of markers specific to astrocytes (GFAP, S100B), microglia (TMEM119, IBA1), AD-associated markers (p-Tau217, β-amyloid) and immune cells such as CD11b+, CD163+, CD4+, and HLA-DRA+, clustered around the β-amyloid plaques.

Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…

Image of a tartaric-acid crystal taken with polarization microscopy. Tartaric acid, a diprotic, aldaric carboxylic acid, is a naturally occurring organic compound notably found in grapes.

偏光显微镜原理

偏光显微镜通常应用于材料科学和地质学领域，根据矿物的折射特性和颜色来识别矿物。在生物学中，偏光显微镜通常用于晶体等双折射结构的识别或成像，或用于植物细胞壁中纤维素和淀粉粒的成像。

What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…