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显微镜科学与教学知识中心

显微镜科学与教学知识中心

显微镜科学与教学知识中心

徕卡显微系统的知识库提供有关显微镜学科的科学研究和教学材料。内容旨在对显微镜初学者、有经验的显微镜操作实践者和使用显微镜的科学家在他们的日常工作和实验有所帮助。这里有探索交互式教程和应用笔记,你可以找到你需要的显微镜的基础知识以及前沿技术——快来加入徕卡显微知识社区,分享您的专业知识!
[Translate to chinese:] Images of smooth muscle cells during wound healing. Courtesy L.S. Shankman, Ph.D., University of Virginia.

平滑肌细胞划痕愈合研究

本文主要讨论如何使用专门配置的徕卡倒置显微镜和台式细胞培养箱轻松、可靠地研究多孔板中培养的平滑肌细胞(SMC)的划痕愈合情况。血管受损后影响SMC增殖和迁移的信号转导情况在医学研究中有重要意义。由于SMC遍布全身,所以对其迁移情况的研究也有助于癌症和损伤的治疗。
GLOW800 Augmented Reality fluorescence in Moyamoya disease treatment

How AR Helps in the Surgical Treatment of Moyamoya Disease

Moyamoya disease is a rare chronic occlusive cerebrovascular disorder characterized by progressive stenosis in the terminal portion of the internal carotid artery and an abnormal vascular network at…
Colon Adenocarcinoma. Four biomarkers shown: NaK, CD8, CD4 and Sma1. T-Cells shown in red and yellow.

多重成像揭示癌症治疗后的生存标志物

结直肠癌是一种高发病率和高死亡率的癌症。目前,术后化疗只能使少数患者获益,因此需要新的工具来筛查患者并识别风险增加的患者。我们利用 Cell DIVE 的多重成像技术对数百名患者的组织样本进行了分析,以揭示癌症治疗后存活率的细微细胞决定因素。
[Translate to chinese:] Clinical case: radial forearm free flap preparation with prelaminated urethra and phalloplasty anastomosis

增强现实荧光技术在桡侧前臂皮瓣游离阴茎成形术中的应用

这个手术中,首席显微外科医生教授及其团队进行了桡侧前臂游离皮瓣阴茎成形术,并使用ICG荧光成像来显示整个皮瓣中从吻合口到阴茎远端的血流。教授展示了增强现实荧光技术除了常见的临床症状外,还能提供检查血流的状态。
Raw widefield and THUNDER image of a mouse dorsal root ganglion with tdTomato (red) expressed in the sensory neurons.

感觉神经元的高对比度快速三维成像

本文讨论了相比传统的宽场显微镜,使用large volume computational clearing(LVCC)技术的THUNDER组织成像系统如何获取背根神经节(DRG)组织高对比度的快速三维成像图,获得感觉神经元更为清晰的解析图像。神经科学研究的一项主要领域集中在感觉神经元对触觉和痛觉的影响方面。深入理解这种现象对于神经系统疾病和疗法的发展具有重要意义。

Minor’s Syndrome Surgical Intervention by Prof. Vincent Darrouzet

Minor’s disease, also called Superior Semicircular Canal Dehiscence (SSCD) or Minor’s syndrome, is a rare disorder of the inner ear that affects hearing and balance. The disease is characterized by…
[Translate to chinese:] Raw widefield (left) and THUNDER (right) image of Ewing Sarcoma cells (SK-ES-1).

肿瘤细胞中有丝分裂纺锤体的成像

本文展示了如何使用THUNDER Imager Tissue和Large Volume Computational…

Formulated Product Characterization with SRS Microscopy

Creams, pastes, gels, emulsions, and tablets are ubiquitous across a wide range of manufacturing sectors from pharmaceuticals and consumer health products to agrochemicals and paint. To improve…

Proveo 8 with intraoperative OCT – a User Evaluation in an University Setting

Optical coherence tomography (OCT) makes structures in the eye visible that lie beneath the surface. When OCT is used intraoperatively, surgeons gain insight into possible pathological changes in the…
Sep 29, 2021
案例研究
外科显微镜
Proveo 8 with intraoperative OCT – a User Evaluation in an University Setting
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