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Epi-Illumination Fluorescence and Reflection-Contrast Microscopy
This article discusses the development of epi-illumination and reflection contrast for fluorescence microscopy concerning life-science applications. Much was done by the Ploem research group…
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Discover how Multiplexed Bioimaging can Advance Cancer Research
Explore multiplexing with up to 60 biomarkers, enabling advanced tumor imaging approaches to gather precise, spatially-resolved single-cell data that helps enhance cancer research and clinical…
![[Translate to chinese:] Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis.](/fileadmin/_processed_/7/3/csm_Prof_Bechrakis_uses_Proveo_8_ceiling_mounted_microscope_with_EnFocus_intraoperative_OCT_dad0be1120.jpg "[Translate to chinese:] Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis.")
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![[Translate to chinese:] Material sample with a large height, size, and weight being observed with an inverted microscope.](/fileadmin/_processed_/f/4/csm_Inverted_microscope_with_large_sample_crop_04c3257c81.jpg "[Translate to chinese:] Material sample with a large height, size, and weight being observed with an inverted microscope.")
工业应用中倒置显微镜相较于正置显微镜的五大优势
使用倒置显微镜时，您需要从下方观察样本，因为倒置显微镜的光学元件位于样本下方，而使用正置显微镜时，您需要从上方观察样本。一直以来，倒置显微镜主要用于生命科学研究，因为重力将样本沉入含有水性溶液的托座底部，从上方则无法观察到太多内容。但近段时间以来，倒置显微镜在工业应用中也变得越来越流行。我们现在一起来了解倒置显微镜在工业应用中的优势。
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共聚焦多色成像在癌症研究和免疫学中的潜力
在本次网络研讨会上，来自莫纳什制药科学研究所的CameronNowell和他的同事将分享他们在多重成像方面的经验，以及他们通过巧妙的共聚焦成像采集和利用FLIM等其他多重成像模式所取得的成果。
![[Translate to chinese:] Keratoplasty of pathologic cornea](/fileadmin/_processed_/6/d/csm_Pathologic_cornea_cb99c6735b.jpg "[Translate to chinese:] Keratoplasty of pathologic cornea")
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![[Translate to chinese:] Acrylonitrile butadiene styrene (ABS) stained with osmium tetroxide (OsO4), sectioned with a DIATOME diamond knife at room temperature, and then imaged with HAADF TEM.](/fileadmin/_processed_/a/b/csm_ABS_stained_with_OsO4_and_sectioned_with_a_DIATOME_diamond_knife_66be7f4863.jpg "[Translate to chinese:] Acrylonitrile butadiene styrene (ABS) stained with osmium tetroxide (OsO4), sectioned with a DIATOME diamond knife at room temperature, and then imaged with HAADF TEM.")
用于材料切片的超薄切片技术
了解这些用于材料切片的超薄切片技术的宝贵见解，并学习如何克服在处理聚合物、金属和脆性材料时遇到的挑战。千万不要错过这个提高您对先进显微镜样品制备方法的认识的机会。
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![[Translate to chinese:] Single cell datasets](/fileadmin/_processed_/8/8/csm_Single_cell_datasets_SPARCS_441a58445d.jpg "[Translate to chinese:] Single cell datasets")
利用 SPARCS 探索亚细胞空间表型
功能日益强大的显微镜可提供信息丰富的各种细胞表型数据。如果与深度学习的最新进展相结合，这将成为在基因筛选中读出感兴趣的生物表型的理想技术。在本网络讲座中，您将了解到空间分辨 CRISPR 筛选 (SPARCS)，这是一种利用自动化高速激光显微切割技术在人类基因组尺度上揭示各种亚细胞空间表型的平台。
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![[Translate to chinese:] Dr. Ozana Moraru shares two primary open-angle glaucoma cases in which trabeculectomy bleb needling was performed using the Leica M844 microscope with EnFocus intraoperative OCT. Image courtesy of Dr. Ozana Moraru.](/fileadmin/_processed_/1/0/csm_Trabeculectomy_bleb_needling_performed_with_Leica_M844_microscope_with_EnFocus_intraoperative_OCT_81e3cbbf3e.jpg "[Translate to chinese:] Dr. Ozana Moraru shares two primary open-angle glaucoma cases in which trabeculectomy bleb needling was performed using the Leica M844 microscope with EnFocus intraoperative OCT. Image courtesy of Dr. Ozana Moraru.")
术中光学显像如何帮助青光眼手术获得更多洞察力
青光眼是导致全球失明的主要原因之一。青光眼手术可以延缓疾病的发展。在青光眼手术过程中，术中光学相干断层扫描（OCT）的使用为眼科外科医生提供了更佳的可视化效果，让他们更深入地了解表面下组织对手术操作的反应。 莫拉鲁博士通过两个原发性开角型青光眼（POAG）的临床病例强调了它的价值。