ATTO-TEC GmbH, Siegen, Germany

ATTO-TEC GmbH was founded in autumn 1999 as a spin-off of the University of Siegen. The decisive factor was the scientific experience of the four founders with organic laser and fluorescent dyes, some of which lasted decades. 

In particular, Prof. Drexhage's research team focused on the synthesis and development of long-wavelength fluorophores for the labeling of biomolecules in the 1990s, as fluorescence-based techniques were established as sensitive detection and analysis methods in the emerging field of life sciences. Thus, in the summer of 2000, the young company was able to present its own market-ready products as a manufacturer of fluorescent dyes for medicine, diagnostics and biology at ACHEMA in Frankfurt am Main.

ATTO-TEC was acquired by Leica in 2024 and is a wholly owned subsidiary of Leica Microsystems.

小鼠成纤维细胞,F-肌动蛋白用 FITC 标记(绿色),微管蛋白用 Cy5 标记(红色),细胞核用 DAPI 标记(蓝色)。图片由德国海德堡马克斯-普朗克医学研究所 Günter Giese 博士提供。

荧光染料应用和特性概述

本文将介绍常用的荧光染料并概述其特性。荧光显微镜借助荧光染料、荧光蛋白或使用抗体的免疫荧光染色来研究特定的细胞成分。由于荧光剂种类繁多,荧光显微镜可用于检查蛋白质、核酸、聚糖、细胞器和其他细胞结构。
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