University of Cincinnati, Department of Ophthalmology

“The Department of Ophthalmology is the preeminent teaching and research center in the Tristate region (southwestern Ohio, northern Kentucky, and southeast Indiana.) The expertise of our faculty over the entire spectrum of ophthalmic sub-specialties makes us the regional center of choice of patients and health care providers. Our faculty members have diverse research interests. Their clinical and basic science investigations regularly yield findings and observations that advance the science and art of ophthalmology and lead to improved patient care.” – From University of Cincinnati, Department of Ophthalmology

https://med.uc.edu/depart/ophtha/home

Fundus photo depicting epiretinal membrane with lamellar macular hole. Image courtesy of Robert A. Sisk, MD, FACS, Cincinnati Eye Institute.

使用光学相干断层扫描改善黄斑孔手术

黄斑裂孔是一种罕见的眼疾，会导致中心视力模糊，影响日常活动。黄斑裂孔通常是由黄斑被牵拉或拉伸而引起的开口，最常见的原因通常是年龄相关的眼部变化。然而，在本病例研究中，Robert A. Sisk博士（医学博士，FACS）介绍了一个小儿眼科病例，其中术中光学相干断层扫描（OCT）为他的手术提供了额外的见解。

Diffuse retinal degeneration with relative macular sparing.

眼部基因治疗视网膜下注射

Leber先天性黑矇（LCA）是一组先天性视网膜营养不良，可导致早年出现重度视力损伤。患者通常表现为眼球震颤、瞳孔反应迟钝或近乎缺失、视力严重下降、畏光和高度远视[1]。眼部基因治疗可极大改善这些患者的视力[2]。通过术中视网膜下注射AAV载体完成基因传递。

术中光学相干断层扫描（OCT）辅助下增生性玻璃体视网膜病变的手术治疗

对患者及其外科医生而言，增生性玻璃体视网膜病变（PVR）是近期孔源性视网膜脱离（RD）后的一大麻烦。尽管初始手术效果极佳，但PVR是导致RD复发的最常见原因，通常导致患者最终视力下降。即使患者最初未发生黄斑脱离，在既往玻璃体切除术后视网膜可再次快速脱离，常累及黄斑，可能需要多次手术来保持视网膜永久附着。