Sophie Veitinger , Dr.

Dr. Sophie Veitinger studied biology at the Ruhr University in Bochum, Germany. In 2005, she received her diploma in zoology and neurobiology. During her PhD thesis at the department of Cell Physiology at the Ruhr University in Bochum, Germany, she investigated purinergic receptors and downstream mitochondrial Ca²⁺ sequestration in murine Sertoli cells. Afterwards she worked in the workgroup for Chemosensation at the RWTH Aachen, Germany. For 2,5 years she was a postdoc at the Institute for Cytobiology and Cytopathology of the Philipps University in Marburg, Germany, where she also coordinated the Bioimaging Facility of the SFB593. Currently, she works as a postdoc at the department of Cell Physiology at the Ruhr University in Bochum, Germany.

Patch pipette touching a murine hippocampal neuron. Image courtesy of A. Aguado, Ruhr University Bochum, Germany.

什么是膜片钳技术？

离子通道的生理学一直是神经科学家感兴趣的一个重要话题。诞生于1970年代的膜片钳技术开启了电生理学家的新时代。它不仅可以对整个细胞进行高分辨率电流记录，还可以对切下的细胞膜片进行高分辨率电流记录。甚至可以研究单通道事件。然而，由于需要复杂且高灵敏的设备，广泛的生物学背景和高水平的实验技能，电生理学仍然是最具挑战性的实验室方法之一。