Irmtraud Steinmetz , Dr.
Irmtraud Steinmetz is Application Manager for the Life Science Division, Leica Microsystems Mannheim. She studied Biology and gained her Ph.D. in Cell Biology. During his time, she gained a lot of experience in the field of microscopy (electron microscopy and histology).
Irmtraud Steinmetz is responsible for customer demonstrations, trainings, worldwide organization of workshops as well as cooperation with reference customers and application letters. She also works in internal projects. Besides the classical confocal microscopy applications, she works in the field Single Molecule Detection Methods with FLIM, FCS and FLCS as well as Multiphoton Microscopy and Electrophysiology.
通过 11 种颜色的光谱分离实现超多标记
荧光显微镜是生命科学研究的基本工具，随着细胞组织和模式生物多色标记策略的发展而不断发展和成熟。分子特异性标记多种物种的能力需要适当的工具来识别样品中的多种荧光标签。严格分离多个标签对于获得有意义的成分、丰度、结构和功能读数至关重要。这种所谓的超多标技术在揭示组织组织、癌症进展、肿瘤免疫相互作用和传染病机制等关键方面已变得十分突出。
电生理学和深层组织成像的新标准
神经和肌肉细胞的功能依赖于通过离子通道流动的离子电流。这些离子通道在细胞生理过程中起着关键作用。研究离子通道的一种方法是使用膜片钳技术。这种方法可以详细研究离子通道，并记录不同类型细胞（主要是神经元、肌纤维或胰岛β细胞）的电活动。膜片钳技术由Erwin Neher和Bert…
