Tatjana Straka , Dr.

Tatjana Straka studied Biotechnology at the University of Applied Sciences in Mannheim and gained her Ph.D. in Biology at the Heidelberg University. During her thesis she worked mainly with mouse skeletal muscle tissue and gained a lot of experience in the field of microscopy. In detail, she applied confocal and digital light-sheet microscopy as well as the corresponding sample preparations in her thesis. In January 2022, she joined Leica Microsystems as a Junior Application Development Specialist.

Spectral separation of 11 fluorophores coupled to polystyrene beads on a STELLARIS confocal system.

通过 11 种颜色的光谱分离实现超多标记

荧光显微镜是生命科学研究的基本工具，随着细胞组织和模式生物多色标记策略的发展而不断发展和成熟。分子特异性标记多种物种的能力需要适当的工具来识别样品中的多种荧光标签。严格分离多个标签对于获得有意义的成分、丰度、结构和功能读数至关重要。这种所谓的超多标技术在揭示组织组织、癌症进展、肿瘤免疫相互作用和传染病机制等关键方面已变得十分突出。