Ana Rubina Perestrelo , Ph.D.

Ana Rubina Perestrelo has started her journey on Madeira Island (Portugal). After finishing her master's studies in Bioengineering and Ph.D. in Biomedical Sciences at the University of Algarve (Portugal), she moved to Brno (Czech Republic), pursuing an experience abroad. Her work in the International Clinical Research Center of St. Anne's University Hospital, entitled multiscale analysis of extracellular matrix remodeling its impact on cardiac cells in heart failure, using both mouse models and patient samples, empowered the development of competencies in cell culture, histology, microscopy, and omics. She then becomes responsible for the microscopy lab maintenance and respective training. Motivated by knowledge application into technology, she takes a role as Technology Scout, focused on technology transfer, IP protection, hospital-industry partnerships, and contractual research.

In October 2020, she joined Leica Microsystems as Product Workflow Manager of Life Science in the Applied Business Unit.

Phase-contrast image of a MDCK-cell culture and its respective confluency measured by the Mateo TL microscope.

如何使用数字化显微镜测定细胞汇合度

本文介绍了如何以一致性的方式测量细胞汇合度。对于生命科学研究领域，例如癌症生物学、干细胞或再生医学，研究通常需要特定生长条件下的细胞。这些条件包括定期检查的细胞形态和汇合度。

Microscope image of cultured cells at the bottom of a dish.

如何对细胞培养进行快速正确的检测

本文介绍了对培养贴壁细胞系进行传代的一般工作流程及步骤说明。哺乳类细胞体外培养是在癌症、药物开发、组织工程、干细胞、疾病细胞和分子生物学等生物医学研究领域进行临床和药物研究的重要模型。要想成功维持细胞系，需要通过控制生长条件来维持细胞生理和表型的稳定性。定期监测细胞生长，对细胞进行传代培养以确保连续性。