Patric Pelzer , Dr.

Patric Pelzer studied Biology and Neuroscience at the University of Cologne, Germany. From Cologne he moved on to Heidelberg to study the characteristics of a defined synapse participating in the processing of olfaction in the mouse brain as a PhD thesis. He employed behavioral conditioning, patch clamping, and immunohistology in conjunction with widefield and confocal microscopy. After a postdoc, Patric joined Leica’s product management team in 2017.

Blood vessel system of a zebrafish larvae

克服显微镜成像移动斑马鱼幼虫时的挑战

Zebrafish is a valuable model organism with many beneficial traits. However, imaging a full organism poses challenges as it is not stationary. Here, this case study shows how zebrafish larvae can be…

Masson-Goldner staining of a hedgehog brain slice.

如何优化您的组织学工作流程

简化您的组织学工作流程。独特的 Fluosync 检测方法内置于Mica中，可实现单次高分辨率 RGB 彩色成像。

如何利用单个系统对组织学荧光样品进行成像

在本集MicaCame中，主持人Lynne Turnbull和Patric Pelzer将带您探寻生物样本染色的历史之旅。他们将解释为什么您通常必须选择为组织学样品或荧光样品选择特定的系统，以及如何利用新的成像技术克服这一点。

多通道活细胞成像注意事项

同时多色成像，确保实验成功：活细胞成像实验是了解动态过程的关键。这类实验使我们能够观察记录活体状态下的细胞，而不会可能因固定或终止不同活体过程而产生干扰性伪影。

Image: Adult rat brain. Neurons (Alexa Fluor488, green), Astrocytes (GFAP, red), Nuclei (DAPI, blue). Image courtesy of Prof. En Xu, Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, China.

多色显微成像：多通道的重要性

多通道一词是指使用多种荧光染料来检查一个样本中的不同元素。多通道成像可以同时观察相关组分和过程，从而为您的观察添加更多背景信息，最终提供更有意义的结果。它还有助于观察采用其他方法可能会遗漏的相互依赖性。