Louise Bertrand

Louise Bertrand

Product Performance Manager, Widefield, North America Technology and Application Support Group – Life Science Division

Louise  joined Leica Microsystems in 2008 as Product Specialist Confocal. A year later Louise added the widefield systems; microscopes, cameras, software. She kept interfacing with customers, sales, applications specialists and field service engineers to deeply understand and provide extensive applications and products support. In 2012, Louise switched and took over the Digital Pathology. In 2014 she started to take over the stereomicroscope lines following by laser microdissection and today, all the widefield products portfolio including CryoCLEM.

Before joining Leica, Louise was Instructor at the Department of Neurobiology & Anatomy at Drexel University, Philadelphia, PA where she taught Medical Neuroscience, managed a core facility and did research on Brain mapping, 3D reconstruction and Image Processing. Louise studied Biochemistry and worked in Developmental Neuroscience, Spinal Cord injury and Neural mechanisms involving functional linking of motor Cortex at Laval University, Quebec, Canada.

清晰对比、无雾的 3D 样本实时图像

历史上,宽场显微镜并不适合对大样本/标本体积进行成像。图像背景(BG)主要来源于观察样本的失焦区域,显著降低了成像系统的对比度、有效动态范围和最大可能的信噪比(SNR)。记录的图像显示出典型的雾霭,并且在许多情况下,无法提供进一步分析所需的细节水平。处理厚三维样本的研究人员要么使用替代显微镜方法,要么尝试通过后处理一系列图像来减少雾霭。
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