Julia Roberti , Dr

Julia Roberti

Julia studied Chemistry at the University of Buenos Aires, where she worked on Photochemistry and Analytical Chemistry. She focused on the characterization of luminescence of lanthanide complexes, and on the development of boron quantification methods for boron neutron capture therapy (BNCT) of cancer. After graduating, she moved to Göttingen to carry out her doctoral research at the Max Planck Institute for Biological Chemistry. She developed in vitro and in situ fluorescence labeling strategies to elucidate the oligomerization and aggregation mechanisms of the Parkinson's disease-associated protein alpha-synuclein. In 2012, she joined EMBL as Humboldt postdoctoral fellow, and applied advanced confocal microscopy and nanoscopy imaging to study chromatin compaction at the interphase-to-mitosis transition. She joined Leica Microsystems in 2017 as Product Manager for advanced confocal imaging.

Spectral separation of 11 fluorophores coupled to polystyrene beads on a STELLARIS confocal system.

通过 11 种颜色的光谱分离实现超多标记

荧光显微镜是生命科学研究的基本工具,随着细胞组织和模式生物多色标记策略的发展而不断发展和成熟。分子特异性标记多种物种的能力需要适当的工具来识别样品中的多种荧光标签。严格分离多个标签对于获得有意义的成分、丰度、结构和功能读数至关重要。这种所谓的超多标技术在揭示组织组织、癌症进展、肿瘤免疫相互作用和传染病机制等关键方面已变得十分突出。

TauInteraction——TauSense新成员,研究分子间相互作用

荧光显微镜是生命科学的重要研究工具之一,用于观察细胞结构和功能。荧光显微镜的一个关键优势在于能够识别多个目标,并能够观察他们之间的相互作用。

A Versatile Palette of Fluorescent Probes

Researchers at the Max Planck Institute for Medical Research in Heidelberg have developed a general strategy to synthesize live-cell compatible fluorogenic probes, and the result are the new MaP (Max…

利用TauSTED在三维空间中观察有丝分裂期间的着丝粒组装

基于 TauSTED(利用寿命的受激发射损耗)技术并结合多根 STED 线(592、660 和 775 纳米),可以呈现有丝分裂纺锤体的三维组织,以及 CENP-C 和 BUB1 的分布情况,从而为着丝粒组装提供深入见解。
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