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超高分辨率显微镜和纳米显微镜

超高分辨率显微镜和纳米显微镜克服了光衍射的限制,以标准共聚焦显微镜从未企及的精细分辨率帮助研究人员研究亚细胞结构。使用 STED 可达到 30 nm 的分辨率,对形态学和亚细胞动态进行纳米级研究。亚衍射共定位分析可揭示前所未见的分子相互作用细节。超高分辨率有助于病毒学、免疫学、神经系统科学和癌症研究领域探索新发现,它正成为光学显微技术新的黄金标准。如今,有了 HyVolution 2、Leica TCS SP8 STED ONE、STED 3X 和 Leica SR GSD 3D,您的深入探索变得前所未有的简单。

观测前所未见的细节,探索生命的真正本质!

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使用 LIGHTNING 最大限度获取每个样品中的信息

LIGHTNING

The maximum of information from each specimen

STED nanoscopy in all 3 dimensions

Leica TCS SP8 STED

STED 纳米显微镜

News

New Light Shed on the Nanodomain Organization of the Endoplasmic Reticulum (ER)

The endoplasmic reticulum (ER) is a continuous membrane organelle in charge of protein synthesis, lipid synthesis and detoxification. The ER structure…

Leica Science Lab
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The Guide to STED Sample Preparation

This guide is intended to help users optimize sample preparation for stimulated emission depletion (STED) nanoscopy, specifically when using the TCS…

Leica Science Lab

Extending Nanoscopy Possibilities with STED and exchangeable fluorophores

When it comes to STED Nanoscopy, keeping high signal-to-noise is key to achieve the best possible resolution in fixed and living cells. This can be…

Leica Science Lab

See More Than Just Your Image

Despite the emergence of new imaging methods in recent years, true 3D resolution is still achieved by Confocal Laser Scanning Microscopy (CLSM).…

Leica Science Lab

Dynamic Endoplasmic Reticulum

The Endoplasmic Reticulum (ER) is a dynamic, reticular or net-like structure consisting of tubules and cisternae that extend throughout the cell and…

Leica Science Lab

Simultaneously Measuring Image Features and Resolution in Live-Cell STED Images

Reliable interpretation and quantification of cellular features in fluorescence microscopy requires an accurate estimate of microscope resolution.…

Leica Science Lab

How to extract Image Information by Adaptive Deconvolution

Confocal Laser Scanning Microscopy (CLSM) is the standard for true 3D resolved fluorescence imaging. Fast optical sectioning using flexible scanning…

Leica Science Lab

Observing Malaria Infection at the Right Spot in the Human Host

Malaria is a life-threatening disease transmitted through the bites of mosquitoes infected with protozoan parasites. The most common and dangerous…

Leica Science Lab

Super-resolved STED spectroscopy

Molecular interactions are key in cellular signalling. They are often ruled or rendered by the mobility of the involved molecules.

Leica Science Lab

STED Nanoscopy at the forefront of cancer research

Alison Dun is the postdoctoral facility manager for the Edinburgh Super-Resolution Imaging Consortium (ESRIC), Heriot-Watt University, Edinburgh, UK.…

Leica Science Lab